Antidromic vasodilatation and the migraine mechanism

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current understanding on pain mechanism in migraine and cluster headache

conclusions migraine and cluster headache have complex pathophysiologies. the exact mechanism causing pain in both conditions is incompletely understood and more research needs to be undertaken in this area. results there is evidence that the trigeminovascular system and neurogenic inflammation play important roles, together with certain areas of the brain, leading to these conditions being ter...

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Antidromic Sensory Conduction

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Migraine headache is not associated with cerebral or meningeal vasodilatation--a 3T magnetic resonance angiography study.

Migraine headache is widely believed to be associated with cerebral or meningeal vasodilatation. Human evidence for this hypothesis is lacking. 3 Tesla magnetic resonance angiography (3T MRA) allows for repetitive, non-invasive, sensitive assessment of intracranial vasodilatation and blood flow. Nitroglycerine (NTG) can faithfully induce migraine attacks facilitating pathophysiological studies ...

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Current Understanding on Pain Mechanism in Migraine and Cluster Headache

CONTEXT Migraine and cluster headache are undoubtedly painful conditions. The respective pathogenesis of these two conditions is incompletely understood. In both cases, the treatments used have largely been empirical and have relied to a much lesser extent on our understanding of the mechanisms causing pain. We hereby review the pain mechanisms in migraine and cluster headache, two of the commo...

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LETTER TO THE EDITOR Migraine headache is not associated with cerebral or meningeal vasodilatation— a 3T magnetic resonance angiography study

Sir, with great interest, we read the article by Schoonman et al. (2008), who claim that ‘in contrast to widespread belief, migraine attacks are not associated with vasodilatation of cerebral or meningeal blood vessels’ and, therefore, ‘future anti-migraine agents may not require vasoconstrictor action’. Whereas the methodology used in this investigation is elegant, we disagree with their claim...

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ژورنال

عنوان ژورنال: The Journal of Headache and Pain

سال: 2011

ISSN: 1129-2369,1129-2377

DOI: 10.1007/s10194-011-0408-3